KD-Validated BUB1B Rabbit Polyclonal Antibody-EnkiLife

KD-Validated BUB1B Rabbit Polyclonal Antibody

Summary

Production Name	KD-Validated BUB1B Rabbit Polyclonal Antibody
Description	KD-Validated antibody
Host	Rabbit
Application	WB
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Rabbit IgG
Clonality	Rabbit pAb
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Purification	Affinity purification

Immunogen

Gene Name	BUB1B
Alternative Names	BUB1B; BUB1 Mitotic Checkpoint Serine/Threonine Kinase B; BUBR1; MAD3L; SSK1; Bub1A; Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 Beta; MAD3/BUB1-Related Protein Kinase; Mitotic Checkpoint Kinase MAD3L; HBUBR1; Budding Uninhibited By Benzimidazoles 1 (Yeast Homolog), Beta; Budding Uninhibited By Benzimidazoles 1 Homolog Beta (Yeast); Budding Uninhibited By Benzimidazoles 1 Homolog Beta; BUB1B, Mitotic Checkpoint Serine/Threonine Kinase; Protein SSK1; EC 2.7.11.1; BUB1beta; MVA1
Gene ID	701
SwissProt ID	O60566

Application

Dilution Ratio	WB 1:2,500-1:5,000
Molecular Weight	Calculated MW: 119.5kDa

Background

This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]

Research Area

Cell Biology,Epigenetics and Nuclear Signaling,Cancer