Summary
| Production Name | KD-Validated DAB2IP Mouse Monoclonal Antibody |
| Description | KD-Validated antibody |
| Host | Mouse |
| Application | WB |
| Reactivity | Human,Mouse,Rat |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | Mouse IgG2a kappa |
| Clonality | Mouse mAb |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Supplied in PBS (pH 7.4) containing 0.02% sodium azide. |
| Purification | Affinity purification |
Immunogen
| Gene Name | DAB2IP |
| Alternative Names | DAB2IP; DAB2 Interacting Protein; AF9Q34; AIP1; KIAA1743; DIP1/2; Disabled Homolog 2-Interacting Protein; DOC-2/DAB2 Interactive Protein; ASK1-Interacting Protein 1; ASK-Interacting Protein 1; DAB2 Interaction Protein; NGAP-Like Protein; AIP-1; DOC-2/DAB-2 Interactive Protein; DAB2-Interacting Protein; ASK-Interacting Protein |
| Gene ID | 153090 |
| SwissProt ID | Q5VWQ8 |
Application
| Dilution Ratio | WB 1:200-1:1,000 |
| Molecular Weight | Calculated MW: 131.6kDa |
Background
DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005 [PubMed 15386433]).[supplied by OMIM, May 2010]
Research Area
Cancer