KO-Validated Apolipoprotein E Recombinant Rabbit Monoclonal Antibody-EnkiLife

KO-Validated Apolipoprotein E Recombinant Rabbit Monoclonal Antibody

Summary

Production Name	KO-Validated Apolipoprotein E Recombinant Rabbit Monoclonal Antibody
Description	KD-Validated antibody
Host	Rabbit
Application	WB,ICC
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	Rabbit IgG
Clonality	Rabbit mAb
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Purification	Affinity purification

Immunogen

Gene Name	APOE
Alternative Names	APOE; Apolipoprotein E; AD2; Alzheimer Disease 2 (APOE*E4-Associated, Late Onset); Apolipoprotein E3; LDLCQ5; APO-E; ApoE4; Apo-E; LPG
Gene ID	348
SwissProt ID	P02649

Application

Dilution Ratio	WB 1:1,000-1:5,000; ICC 1:100-1:1,000
Molecular Weight	Calculated MW: 36.2kDa

Background

The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016]

Research Area

Neuroscience,Cardiovascular,Neuroscience,Stem Cells,Signal Transduction,Developmental Biology,Cancer,Metabolism