Name: MLKL (5E3) Mouse Monoclonal Antibody
Brand: Enkilife Limited
SKU: AMM00761
Price: 150 USD
Availability: InStock
Rating: 5 (1 reviews)

MLKL (5E3) Mouse Monoclonal Antibody

Cat: AMM00761

Size:50μL Price:$150
Size:100μL Price:$280
Size:200μL Price:$520
Application:IHC
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:MLKL Category: Mouse Monoclonal Antibody Tags: Unconjugated, Signal Transduction, Mouse, IHC, Human

Datasheet

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Summary

Production Name	MLKL (5E3) Mouse Monoclonal Antibody
Description	Mouse monoclonal Antibody
Host	Mouse
Application	IHC
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG1
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.
Purification	Affinity Purification

Immunogen

Gene Name	MLKL
Alternative Names	MLKL
Gene ID	197259
SwissProt ID	Q8NB16

Application

Dilution Ratio	IHC 1:50-1:100
Molecular Weight	-

Background

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Research Area

Signal Transduction