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PHF8 Rabbit Monoclonal Antibody

PHF8 Rabbit Monoclonal Antibody

Cat: AMRe84004
Size:20μL Price:$98
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,ICC,IP
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:PHF8 Category: Recombinant Monoclonal Antibody Tags:

Summary

Production Name

PHF8 Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,ICC,IP

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol.

Purification

Affinity Purification

 

Immunogen

Gene Name

PHF8

Alternative Names

Histone lysine demethylase PHF8; MRXSSD; PHD finger protein 8; PHF8; ZNF422;;PHF8

Gene ID

SwissProt ID

Q9UPP1

 

Application

Dilution Ratio

WB 1:1000-1:2000,ICC 1:50-1:200,IP 1:20-1:50

Molecular Weight

Calculated MW: 118 kDa ; Observed MW: 140 kDa

 

Background

Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA transcription and brain development. Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K9Me2), dimethylated H3 'Lys-27' (H3K27Me2) and monomethylated histone H4 'Lys-20' residue (H4K20Me1). Acts as a transcription activator as H3K9Me1, H3K9Me2, H3K27Me2 and H4K20Me1 are epigenetic repressive marks. Involved in cell cycle progression by being required to control G1-S transition.

 

Research Area

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