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Phospho-MLKL(S345) Rabbit Monoclonal Antibody

Phospho-MLKL(S345) Rabbit Monoclonal Antibody

Cat: AMRe83707
Size:20μL Price:$98
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,IP
Reactivity:Mouse
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:Phospho-MLKL(S345) Category: Recombinant Monoclonal Antibodies Tags:

Summary

Production Name

Phospho-MLKL(S345) Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IP

Reactivity

Mouse

 

Performance

Conjugation

Unconjugated

Modification

Phosphorylated

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol.

Purification

Affinity Purification

 

Immunogen

Gene Name

Phospho-MLKL(S345)

Alternative Names

hMLKL ; Mixed lineage kinase domain like; Mixed lineage kinase domain like protein; Mixed lineage kinase domain like pseudokinase;;p-Mlkl (S345)

Gene ID

SwissProt ID

Q9D2Y4(mouse)Q8NB16(Human)

 

Application

Dilution Ratio

WB 1:1000-1:2000,IP 1:20-1:50

Molecular Weight

54 kDa

 

Background

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process.Does not have protein kinase activity.Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage.

 

Research Area

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