Name: SIGIRR Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: AMRe87787
Price: 168 USD
Availability: InStock
Rating: 5 (1 reviews)

SIGIRR Rabbit Monoclonal Antibody

Cat: AMRe87787

Size:50μL Price:$168
Size:100μL Price:$300
Application:WB
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:SIGIRR Category: Recombinant Monoclonal Antibody Tags: Rabbit, Unconjugated, WB, Human, Mouse, Rat

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Summary

Production Name	SIGIRR Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt.
Purification	Affinity Purification

Immunogen

Gene Name	SIGIRR
Alternative Names	TIR8; IL-1R8
Gene ID	59307
SwissProt ID	Q6IA17

Application

Dilution Ratio	WB 1:1000-1:5000
Molecular Weight	Calculated MW:46 kDa; Observed MW:75-100 kDa

Background

Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.

Research Area