Summary
Performance
Immunogen
Application
Background
Inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex (By similarity). In complex with CUL3, involved in ubiquitination of BMI1, H2AFY and DAXX, and probably also in ubiquitination and proteasomal degradation of Gli2 or Gli3.
Research Area
Epigenetics and Nuclear Signaling; Transcription; Domain Families; Forkhead Box; FOXO
