TXNRD1 (6I18) Rabbit Monoclonal Antibody

TXNRD1 (6I18) Rabbit Monoclonal Antibody

Cat: AMRe19460
Size:50μL Price:$128
Size:100μL Price:$230
Size:200μL Price:$380
Application:WB,IHC,IF-P
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:TXNRD1 Category: Recombinant Monoclonal Antibody Tags:

Summary

Production Name

TXNRD1 (6I18) Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,IF-P

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Purification

Affinity purification

 

Immunogen

Gene Name

TXNRD1

Alternative Names

GRIM12; KDRF; KM 102 derived reductase like factor; xidoreductase; Thioredoxin reductase 1; TR1; TRXR1; TXNR; TXNRD1

Gene ID

7296

SwissProt ID

Q16881

 

Application

Dilution Ratio

WB 1:1000-1:5000,IHC 1:50-1:100,IF-P 1:50-1:100

Molecular Weight

71kDa

 

Background

Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid. Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.

 

Research Area

Signal Transduction

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