mSin3A Rabbit Monoclonal Antibody

mSin3A Rabbit Monoclonal Antibody

Cat: AMRe83980
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,IHC,ICC/IF,ICC,FC
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:mSin3A Category: Recombinant Monoclonal Antibody Tags:

Summary

Production Name

mSin3A Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,ICC/IF,ICC,FC

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol.

Purification

Affinity Purification

 

Immunogen

Gene Name

mSin3A

Alternative Names

Histone deacetylase complex subunit Sin 3a; Paired amphipathic helix protein Sin 3a; SIN3 homolog A;;SIN3A

Gene ID

SwissProt ID

Q96ST3

 

Application

Dilution Ratio

WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200,FC 1:20-1:100

Molecular Weight

Calculated MW: 145 kDa ; Observed MW: 150 kDa

 

Background

Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation.

 

Research Area

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